{"id":5542,"date":"2025-02-16T17:02:13","date_gmt":"2025-02-16T08:02:13","guid":{"rendered":"https:\/\/tuat-chemphys.net\/?p=5542"},"modified":"2026-04-17T06:47:18","modified_gmt":"2026-04-16T21:47:18","slug":"%e4%b8%96%e7%95%8c%e5%88%9d%ef%bc%81%e7%b9%ad%e3%82%92%e4%bd%bf%e3%82%8f%e3%81%aa%e3%81%84%e3%80%8c%e3%82%ab%e3%82%a4%e3%82%b3%e7%b5%b9%e7%b3%b8%e8%85%ba%e3%80%8d%e3%81%8b%e3%82%89%e3%81%ae%e3%82%b7","status":"publish","type":"post","link":"https:\/\/tuat-chemphys.net\/?p=5542","title":{"rendered":"\u4e16\u754c\u521d\uff01\u7e6d\uff08\u307e\u3086\uff09\u3092\u4f7f\u308f\u306a\u3044\u300c\u30ab\u30a4\u30b3\u7d79\u7cf8\u817a\u300d\u304b\u3089\u306e\u30b7\u30eb\u30af\u6750\u6599\u88fd\u9020\u6cd5 Groundbreaking Research on Silk Gland Extraction and Processing"},"content":{"rendered":"\n<p class=\"has-text-align-center has-accent-color has-pale-ocean-gradient-background has-text-color has-background has-link-color has-normal-font-size wp-elements-aad19746e6d0dddf83feedeb48460bec\"><strong>Recorded video on this research \u9332\u753b\u3055\u308c\u305f\u7814\u7a76\u767a\u8868\uff1a<a href=\"https:\/\/wp.me\/p10HOa-7QX\">https:\/\/wp.me\/p10HOa-7QX<\/a><\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Research Highlight<\/h3>\n\n\n\n<p>A research team (TUAT Lenggoro Lab and Pentalink Co. Ltd) has developed a revolutionary method to extract silk glands directly from silkworms using a scalable wet milling process. This technique bypasses the traditional cocoon-based silk production, offering a more efficient and sustainable approach to creating silk-based materials that could replace fossil fuel-derived plastics. \u6771\u4eac\u8fb2\u5de5\u5927\u5b66\uff08\u30ec\u30f3\u30b4\u30ed\u7814\u7a76\u5ba4\uff09\u3068\u30b7\u30eb\u30af\u6750\u6599\u306e\u30b9\u30bf\u30fc\u30c8\u30a2\u30c3\u30d7\u4f01\u696d\uff08\u30da\u30f3\u30bf\u30ea\u30f3\u30af\uff09\u306e\u7814\u7a76\u30c1\u30fc\u30e0\u306f\u3001\u30ab\u30a4\u30b3\u306e\u7e6d\uff08\u307e\u3086\uff09\u3092\u4f7f\u308f\u305a\u306b\u76f4\u63a5\u300c\u7d79\u7cf8\u817a\u300d\u304b\u3089\u30b7\u30eb\u30af\u6750\u6599\u3092\u88fd\u9020\u3059\u308b\u4e16\u754c\u521d\u306e\u624b\u6cd5\u3092\u958b\u767a\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u6280\u8853\u306f\u3001\u5316\u77f3\u71c3\u6599\u7531\u6765\u30d7\u30e9\u30b9\u30c1\u30c3\u30af\u306e\u4ee3\u66ff\u3068\u306a\u308b\u6301\u7d9a\u53ef\u80fd\u306a\u30d0\u30a4\u30aa\u6750\u6599\u306e\u751f\u7523\u306b\u9769\u547d\u3092\u3082\u305f\u3089\u3059\u53ef\u80fd\u6027\u3092\u79d8\u3081\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">The Challenge<\/h3>\n\n\n\n<p>The mid-21st century presents humanity with a critical challenge: transitioning from fossil fuel-dependent industrial structures to sustainable, low-carbon alternatives. Currently, about 90% of fossil fuels are used for energy production, with the remainder used for materials like plastics. As we address the climate crisis, reimagining how we produce materials becomes essential. Natural materials refined over millennia, like silk, offer promising alternatives if we can develop modern, efficient production techniques. 21 \u4e16\u7d00\u534a\u3070\u3001\u4eba\u985e\u306f\u5316\u77f3\u71c3\u6599\u306b\u4f9d\u5b58\u3059\u308b\u7523\u696d\u69cb\u9020\u304b\u3089\u6301\u7d9a\u53ef\u80fd\u306a\u4f4e\u70ad\u7d20\u4ee3\u66ff\u7269\u3078\u306e\u79fb\u884c\u3068\u3044\u3046\u91cd\u5927\u306a\u8ab2\u984c\u306b\u76f4\u9762\u3057\u3066\u3044\u307e\u3059\u3002\u73fe\u5728\u3001\u5316\u77f3\u71c3\u6599\u306e\u7d04 90% \u306f\u30a8\u30cd\u30eb\u30ae\u30fc\u751f\u7523\u306b\u4f7f\u7528\u3055\u308c\u3001\u6b8b\u308a\u306f\u30d7\u30e9\u30b9\u30c1\u30c3\u30af\u306a\u3069\u306e\u6750\u6599\u306b\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u6c17\u5019\u5371\u6a5f\u306b\u5bfe\u51e6\u3059\u308b\u306b\u306f\u3001\u6750\u6599\u306e\u751f\u7523\u65b9\u6cd5\u3092\u518d\u8003\u3059\u308b\u3053\u3068\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u30b7\u30eb\u30af\u306e\u3088\u3046\u306b\u3001\u4f55\u5343\u5e74\u3082\u304b\u3051\u3066\u7cbe\u88fd\u3055\u308c\u3066\u304d\u305f\u5929\u7136\u7d20\u6750\u306f\u3001\u73fe\u4ee3\u7684\u3067\u52b9\u7387\u7684\u306a\u751f\u7523\u6280\u8853\u3092\u958b\u767a\u3067\u304d\u308c\u3070\u3001\u6709\u671b\u306a\u4ee3\u66ff\u7269\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>INNOVATIVE APPROACH<\/strong><\/h2>\n\n\n\n<p>Silk from the silkworm&nbsp;<em>Bombyx mori<\/em>&nbsp;has traditionally been valued for its excellent texture and luster in textiles. Beyond textiles, silk shows tremendous promise as a &#8220;plastic alternative&#8221; due to its:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Versatile Processability: Silk can be formed into various shapes and structures, making it suitable for many applications currently dominated by plastics. \u30b7\u30eb\u30af\u306f\u3055\u307e\u3056\u307e\u306a\u5f62\u3084\u69cb\u9020\u306b\u6210\u5f62\u3067\u304d\u308b\u305f\u3081\u3001\u73fe\u5728\u306f\u30d7\u30e9\u30b9\u30c1\u30c3\u30af\u304c\u4e3b\u6d41\u3068\u306a\u3063\u3066\u3044\u308b\u591a\u304f\u306e\u7528\u9014\u306b\u9069\u3057\u3066\u3044\u307e\u3059\u3002<\/li>\n\n\n\n<li>Biocompatibility: Silk is compatible with living tissues, making it ideal for medical applications where plastics might cause adverse reactions. \u30b7\u30eb\u30af\u306f\u751f\u4f53\u7d44\u7e54\u3068\u9069\u5408\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u30d7\u30e9\u30b9\u30c1\u30c3\u30af\u304c\u6709\u5bb3\u306a\u53cd\u5fdc\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308b\u533b\u7642\u7528\u9014\u306b\u6700\u9069\u3067\u3059\u3002<\/li>\n\n\n\n<li>Controllable Biodegradability: Unlike many plastics that persist in the environment for centuries, the breakdown of silk materials can be engineered to occur when desired. \u4f55\u4e16\u7d00\u306b\u3082\u308f\u305f\u3063\u3066\u74b0\u5883\u4e2d\u306b\u6b8b\u7559\u3059\u308b\u591a\u304f\u306e\u30d7\u30e9\u30b9\u30c1\u30c3\u30af\u3068\u306f\u7570\u306a\u308a\u3001\u30b7\u30eb\u30af\u7d20\u6750\u306e\u5206\u89e3\u306f\u3001\u5fc5\u8981\u306a\u3068\u304d\u306b\u767a\u751f\u3059\u308b\u3088\u3046\u306b\u8a2d\u8a08\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Makes This Method Special?<\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><strong>Traditional Silk Processing<\/strong> (\u5f93\u6765\u6cd5)<\/td><td><strong>&nbsp;Direct Extraction Method<\/strong><\/td><\/tr><tr><td>Growing silkworms until they spin cocoons \u30ab\u30a4\u30b3\u304c\u7e6d\u3092\u7d21\u3050\u307e\u3067\u80b2\u3066\u308b<\/td><td>Preserving silkworms through ethanol treatment or freezing\u3000\u30a8\u30bf\u30ce\u30fc\u30eb\u51e6\u7406\u3084\u51b7\u51cd\u306b\u3088\u308b\u30ab\u30a4\u30b3\u306e\u4fdd\u5b58<\/td><\/tr><tr><td>Harvesting cocoons \u7e6d\u3092\u53ce\u7a6b\u3059\u308b<\/td><td>Using a wet milling process to extract silk glands directly\u3000\u6e7f\u5f0f\u7c89\u7815\u6cd5\u3092\u7528\u3044\u3066\u7d79\u7cf8\u817a\u3092\u76f4\u63a5\u62bd\u51fa\u3059\u308b<\/td><\/tr><tr><td>Dissolving cocoon fibers in a solution (lithium bromide, etc.) \u81ed\u5316\u30ea\u30c1\u30a6\u30e0\u7b49\u306e\u6eb6\u6db2\u3067\u7e6d\u306e\u7e4a\u7dad\u3092\u6eb6\u304b\u3059<\/td><td>Separating silk glands from other tissues through density separation\u3000\u5bc6\u5ea6\u5206\u96e2\u306b\u3088\u308a\u7d79\u7cf8\u817a\u3092\u4ed6\u306e\u7d44\u7e54\u304b\u3089\u5206\u96e2\u3059\u308b<\/td><\/tr><tr><td>Performing dialysis to remove the chemicals \u5316\u5b66\u7269\u8cea\u3092\u9664\u53bb\u3059\u308b\u305f\u3081\u306b\u900f\u6790\u3092\u884c\u3046<\/td><td>Degumming to remove sericin (the outer coating)\u3000\u30bb\u30ea\u30b7\u30f3\uff08\u5916\u5074\u306e\u30b3\u30fc\u30c6\u30a3\u30f3\u30b0\uff09\u3092\u9664\u53bb\u3059\u308b\u8131\u30ac\u30e0<\/td><\/tr><tr><td>Further processing to create usable materials \u4f7f\u7528\u53ef\u80fd\u306a\u6750\u6599\u3092\u4f5c\u6210\u3059\u308b\u305f\u3081\u306e\u3055\u3089\u306a\u308b\u51e6\u7406<\/td><td>Dry-milling to create silk fibroin powder\u3000\u4e7e\u5f0f\u7c89\u7815\u306b\u3088\u308b\u30b7\u30eb\u30af\u30d5\u30a3\u30d6\u30ed\u30a4\u30f3\u7c89\u672b\u306e\u88fd\u9020<\/td><\/tr><tr><td><\/td><td><\/td><\/tr><tr><td>This method is labor-intensive and requires harsh chemicals.\u3000\u3053\u306e\u65b9\u6cd5\u306f\u52b4\u50cd\u96c6\u7d04\u7684\u3067\u3042\u308a\u3001\u5f37\u529b\u306a\u5316\u5b66\u85ac\u54c1\u3092\u5fc5\u8981\u3068\u3057\u307e\u3059\u3002<\/td><td>This method is more efficient, scalable, and requires fewer harsh chemicals.\u3000\u3053\u306e\u65b9\u6cd5\u306f\u3088\u308a\u52b9\u7387\u7684\u3067\u62e1\u5f35\u6027\u304c\u3042\u308a\u3001\u5fc5\u8981\u306a\u5f37\u529b\u306a\u5316\u5b66\u7269\u8cea\u3082\u5c11\u306a\u304f\u306a\u308a\u307e\u3059\u3002<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><\/h3>\n\n\n\n<h2 class=\"wp-block-heading\">Why This Matters\u3000\u306a\u305c\u3053\u308c\u304c\u91cd\u8981\u306a\u306e\u304b: Environmental Impact<\/h2>\n\n\n\n<p>This research contributes to the global effort to transition away from fossil fuel-derived materials. By developing efficient methods to process natural materials like silk, we&#8217;re helping to create alternatives to petroleum-based plastics that can biodegrade safely in the environment.\u3000\u3053\u306e\u7814\u7a76\u306f\u3001\u5316\u77f3\u71c3\u6599\u7531\u6765\u306e\u7d20\u6750\u304b\u3089\u306e\u8131\u5374\u3092\u76ee\u6307\u3059\u4e16\u754c\u7684\u306a\u53d6\u308a\u7d44\u307f\u306b\u8ca2\u732e\u3057\u3066\u3044\u307e\u3059\u3002\u30b7\u30eb\u30af\u306a\u3069\u306e\u5929\u7136\u7d20\u6750\u3092\u52a0\u5de5\u3059\u308b\u52b9\u7387\u7684\u306a\u65b9\u6cd5\u3092\u958b\u767a\u3059\u308b\u3053\u3068\u3067\u3001\u74b0\u5883\u4e2d\u3067\u5b89\u5168\u306b\u751f\u5206\u89e3\u3067\u304d\u308b\u77f3\u6cb9\u7531\u6765\u306e\u30d7\u30e9\u30b9\u30c1\u30c3\u30af\u306e\u4ee3\u66ff\u54c1\u306e\u958b\u767a\u306b\u8ca2\u732e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>Publication in Journal:<\/strong> <\/p>\n\n\n\n<p><mark style=\"background-color:rgba(0, 0, 0, 0);color:#660703\" class=\"has-inline-color\"><strong>Milling-Based Extraction and Characterization of Bombyx mori Silk Glands and Fibroin Powder for Biomaterial Use<\/strong>.<\/mark> <a href=\"https:\/\/doi.org\/10.1016\/j.apt.2025.104820\">https:\/\/doi.org\/10.1016\/j.apt.2025.104820<\/a> (Supplementary data: <a href=\"https:\/\/doi.org\/10.1016\/j.apt.2025.104820\">https:\/\/doi.org\/10.1016\/j.apt.2025.104820<\/a>)<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"701\" height=\"531\" data-attachment-id=\"5543\" data-permalink=\"https:\/\/tuat-chemphys.net\/?attachment_id=5543\" data-orig-file=\"https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2025\/02\/yoshida-abstract-image2025.jpg?fit=701%2C531&amp;ssl=1\" data-orig-size=\"701,531\" data-comments-opened=\"0\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"yoshida-abstract-image2025\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2025\/02\/yoshida-abstract-image2025.jpg?fit=701%2C531&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2025\/02\/yoshida-abstract-image2025.jpg?resize=701%2C531&#038;ssl=1\" alt=\"\" class=\"wp-image-5543\" srcset=\"https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2025\/02\/yoshida-abstract-image2025.jpg?w=701&amp;ssl=1 701w, https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2025\/02\/yoshida-abstract-image2025.jpg?resize=300%2C227&amp;ssl=1 300w\" sizes=\"auto, (max-width: 701px) 100vw, 701px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center\"><\/h2>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/wp.me\/p10HOa-7QX\"><strong>Recorded video on this research <\/strong>as PhD public presentation<strong> \u9332\u753b\u3055\u308c\u305f\u535a\u58eb\u516c\u8074\u4f1a\uff1ahttps:\/\/wp.me\/p10HOa-7QX<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3053\u306e\u753b\u671f\u7684\u306a\u6280\u8853\u306f\u3001\u5316\u77f3\u71c3\u6599\u7531\u6765\u30d7\u30e9\u30b9\u30c1\u30c3\u30af\u306e\u4ee3\u66ff\u3068\u306a\u308b\u6301\u7d9a\u53ef\u80fd\u306a\u30d0\u30a4\u30aa\u6750\u6599\u306e\u751f\u7523\u306b\u9769\u547d\u3092\u3082\u305f\u3089\u3059\u53ef\u80fd\u6027\u3092\u79d8\u3081\u3066\u3044\u307e\u3059\u3002This breakthrough offers 30% less wasteful alternative to conventional silk production methods.<\/p>\n","protected":false},"author":1,"featured_media":5543,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[9],"tags":[12,13,15],"class_list":["post-5542","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","tag-energy-conversion-optimization","tag-eco-friendly-systems","tag-environmental-technology"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2025\/02\/yoshida-abstract-image2025.jpg?fit=701%2C531&ssl=1","jetpack_sharing_enabled":true,"jetpack-related-posts":[{"id":5459,"url":"https:\/\/tuat-chemphys.net\/?p=5459","url_meta":{"origin":5542,"position":0},"title":"PhD \u516c\u8074\u4f1a \u201cSilk Production Without Cocoons\u201d \u7e6d\uff08\u307e\u3086\uff09\u3092\u4f7f\u308f\u306a\u3044\u7d79\u751f\u7523 (10 Feb.)","author":"unet","date":"2025-02","format":false,"excerpt":"The study demonstrates a novel method of extracting silk proteins directly from silkworm silk glands using milling techniques. \u672c\u7814\u7a76\u306f\u3001\u7c89\u7815\u6280\u8853\u3092\u7528\u3044\u3066\u30ab\u30a4\u30b3\u306e\u7d79\u7cf8\u817a\u304b\u3089\u76f4\u63a5\u7d79\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u62bd\u51fa\u3059\u308b\u65b0\u3057\u3044\u65b9\u6cd5\u3092\u5b9f\u8a3c\u3059\u308b\u3002","rel":"","context":"In &quot;Doctoral Thesis \u535a\u58eb\u8ad6\u6587&quot;","block_context":{"text":"Doctoral Thesis 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