{"id":5255,"date":"2024-11-30T19:09:00","date_gmt":"2024-11-30T10:09:00","guid":{"rendered":"https:\/\/tuat-chemphys.net\/?p=5255"},"modified":"2024-11-30T19:09:00","modified_gmt":"2024-11-30T10:09:00","slug":"enhancing-crystal-quality-with-high-shear-stress-in-continuous-flow-%e9%80%a3%e7%b6%9a%e6%b5%81%e5%8b%95%e4%b8%ad%e3%81%ae%e9%ab%98%e3%81%9b%e3%82%93%e6%96%ad%e5%bf%9c%e5%8a%9b%e3%81%a7%e7%b5%90","status":"publish","type":"post","link":"https:\/\/tuat-chemphys.net\/?p=5255","title":{"rendered":"Enhancing Crystal Quality with High Shear Stress in Continuous Flow \u9023\u7d9a\u6d41\u52d5\u4e2d\u306e\u9ad8\u305b\u3093\u65ad\u5fdc\u529b\u3067\u7d50\u6676\u54c1\u8cea\u3092\u5411\u4e0a"},"content":{"rendered":"\n<h6 class=\"wp-block-heading has-text-align-center\" id=\"englishversion\">English follows Japanese<\/h6>\n\n\n\n<h3 class=\"wp-block-heading has-text-align-center\" id=\"titleenhancingcrystalqualitywithhighshearstressincontinuousflow\">\u9023\u7d9a\u6d41\u52d5\u4e2d\u306e\u9ad8\u305b\u3093\u65ad\u5fdc\u529b\u3067\u7d50\u6676\u54c1\u8cea\u3092\u5411\u4e0a<\/h3>\n\n\n\n<p>\u6edd\u5c71\u7814\u7a76\u5ba4\u306f\u3001\u53cd\u5fdc\u6027\u7d50\u6676\u5316\u4e2d\u306e\u7d50\u6676\u7c92\u5b50\u306e\u54c1\u8cea\u3092\u5411\u4e0a\u3055\u305b\u308b\u65b0\u3057\u3044\u65b9\u6cd5\u3092\u958b\u767a\u3057\u307e\u3057\u305f\u3002\u30c6\u30a4\u30e9\u30fc\u6e26\u6d41\u3068\u547c\u3070\u308c\u308b\u9ad8\u305b\u3093\u65ad\u5fdc\u529b\u3092\u4f34\u3046\u9023\u7d9a\u6d41\u52d5\u3092\u4f7f\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u76f8\u56f3\u4e0a\u306e\u7570\u306a\u308b\u64cd\u4f5c\u70b9\u304c\u7d50\u6676\u54c1\u8cea\u306b\u3069\u306e\u3088\u3046\u306b\u5f71\u97ff\u3059\u308b\u304b\u3092\u7814\u7a76\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u65b9\u6cd5\u306f\u3001\u4e00\u8cab\u3057\u305f\u6761\u4ef6\u3092\u7dad\u6301\u3057\u3001\u7c92\u5b50\u306e\u51dd\u96c6\u3092\u9632\u3050\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7814\u7a76\u3067\u306f\u3001\u6eb6\u6db2\u306epH\u3084\u904e\u98fd\u548c\u5ea6\u306a\u3069\u306e\u8981\u56e0\u304c\u7d50\u6676\u306e\u30a2\u30b9\u30da\u30af\u30c8\u6bd4\uff08\u7e26\u6a2a\u306e\u6bd4\u7387\u3092\u8868\u3059\u6307\u6a19\uff09\u3084\u30b5\u30a4\u30ba\u5206\u5e03\u306b\u5927\u304d\u304f\u5f71\u97ff\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u8981\u56e0\u3092\u8003\u616e\u3057\u305f\u64cd\u4f5c\u6226\u7565\u3092\u614e\u91cd\u306b\u8a2d\u8a08\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u9ad8\u54c1\u8cea\u306a\u7d50\u6676\u7c92\u5b50\u3092\u751f\u6210\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3057\u305f\u3002\u3053\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u306f\u3001\u64cd\u4f5c\u70b9\u3068\u7d50\u6676\u54c1\u8cea\u306e\u95a2\u4fc2\u3092\u660e\u78ba\u306b\u3057\u3001\u7d50\u6676\u5316\u30d7\u30ed\u30bb\u30b9\u3092\u6539\u5584\u3059\u308b\u305f\u3081\u306e\u6709\u671b\u306a\u6226\u7565\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"titleenhancingcrystalqualitywithhighshearstressincontinuousflow\">Enhancing Crystal Quality with High Shear Stress in Continuous Flow<\/h3>\n\n\n\n<p>Takiyama Research Group has developed a new method to improve the quality of crystalline particles during reactive crystallization. By using a continuous flow with high shear stress, known as Taylor vortex flow, they were able to study how different operation points on the phase diagram affect crystal quality. This method helps to maintain consistent conditions and prevent particle agglomeration.<\/p>\n\n\n\n<p>The study found that factors like solution pH and supersaturation significantly impact the aspect ratio and size distribution of the crystals. By carefully designing an operation strategy that considers these factors, the researchers were able to produce higher quality crystalline particles. This approach clarifies the relationship between operation points and crystal quality, offering a promising strategy for improving crystallization processes.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"723\" height=\"540\" data-attachment-id=\"5257\" data-permalink=\"https:\/\/tuat-chemphys.net\/?attachment_id=5257\" data-orig-file=\"https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2024\/11\/image-11.png?fit=723%2C540&amp;ssl=1\" data-orig-size=\"723,540\" data-comments-opened=\"0\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"image\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2024\/11\/image-11.png?fit=723%2C540&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2024\/11\/image-11.png?resize=723%2C540&#038;ssl=1\" alt=\"\" class=\"wp-image-5257\" style=\"width:405px;height:auto\" srcset=\"https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2024\/11\/image-11.png?w=723&amp;ssl=1 723w, https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2024\/11\/image-11.png?resize=300%2C224&amp;ssl=1 300w\" sizes=\"auto, (max-width: 723px) 100vw, 723px\" \/><\/figure>\n<\/div>\n\n\n<figure class=\"wp-block-image size-large\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"810\" height=\"161\" data-attachment-id=\"5259\" data-permalink=\"https:\/\/tuat-chemphys.net\/?attachment_id=5259\" data-orig-file=\"https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2024\/11\/image-12.png?fit=1088%2C217&amp;ssl=1\" data-orig-size=\"1088,217\" data-comments-opened=\"0\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"image\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2024\/11\/image-12.png?fit=810%2C161&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2024\/11\/image-12.png?resize=810%2C161&#038;ssl=1\" alt=\"\" class=\"wp-image-5259\" srcset=\"https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2024\/11\/image-12.png?resize=1024%2C204&amp;ssl=1 1024w, https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2024\/11\/image-12.png?resize=300%2C60&amp;ssl=1 300w, https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2024\/11\/image-12.png?resize=768%2C153&amp;ssl=1 768w, https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2024\/11\/image-12.png?w=1088&amp;ssl=1 1088w\" sizes=\"auto, (max-width: 810px) 100vw, 810px\" \/><\/figure>\n\n\n\n<p><strong>Investigating the effect of operation points on crystal quality in reactive crystallization using continuous flow with high shear stress<\/strong><br>Shuntaro Amari, Chinami Sugawara, Ryo Harada, Shoji Kudo, Hiroshi Takiyama<br><a href=\"https:\/\/doi.org\/10.1016\/j.cherd.2021.09.030\">https:\/\/doi.org\/10.1016\/j.cherd.2021.09.030<\/a><\/p>\n\n\n\n<p><strong>Highlights<\/strong><br>\u2022Crystal quality for reactive crystallization is studied using continuous process.<br>\u2022Continuous flow with high shear stress is employed to efficiently mix feed solutions.<br>\u2022Effect of operation points on crystal quality is revealed using a continuous process.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A method to improve crystalline particle quality during reactive crystallization using high shear stress in continuous flow. Maintaining consistent conditions and prevent agglomeration, leading to better crystal quality by considering factors like solution pH and supersaturation. 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Seminar] Controlling Medicine Crystals with Fluid Dynamics: The Power of Taylor-Couette Vortex\u3010\u535a\u58eb\u8ad6\u6587\u516c\u8074\u4f1a\u3011\u6d41\u4f53\u529b\u5b66\u3067\u85ac\u3092\u5275\u308b\uff1a\u30c6\u30a4\u30e9\u30fc\u30fb\u30af\u30a8\u30c3\u30c8\u6d41\u308c\u306b\u3088\u308b\u7d50\u6676\u306e\u5236\u5fa1 (2\/9 10:30)","author":"unet","date":"2026-02","format":false,"excerpt":"This research explores how specialized \"vortex\" flows can be used to create high-quality medicinal crystals. \u533b\u85ac\u54c1\u88fd\u9020\u306e\u65b0\u3057\u3044\u624b\u6cd5\u306b\u95a2\u3059\u308b\u535a\u58eb\u8ad6\u6587\u516c\u8074\u4f1a\u3092\u958b\u50ac\u3057\u307e\u3059\u3002\u672c\u7814\u7a76\u306f\u3001\u7279\u6b8a\u306a\u300c\u6e26\u300d\u306e\u6d41\u308c\u3092\u5229\u7528\u3057\u3066\u3001\u9ad8\u54c1\u8cea\u306a\u85ac\u306e\u7d50\u6676\u3092\u4f5c\u308a\u51fa\u3059\u6280\u8853\u306b\u3064\u3044\u3066\u63a2\u6c42\u3057\u3066\u3044\u307e\u3059\u3002","rel":"","context":"In &quot;Doctoral Thesis \u535a\u58eb\u8ad6\u6587&quot;","block_context":{"text":"Doctoral Thesis \u535a\u58eb\u8ad6\u6587","link":"https:\/\/tuat-chemphys.net\/?cat=22"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2026\/02\/image-2.png?fit=593%2C397&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2026\/02\/image-2.png?fit=593%2C397&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2026\/02\/image-2.png?fit=593%2C397&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":6478,"url":"https:\/\/tuat-chemphys.net\/?p=6478","url_meta":{"origin":5255,"position":1},"title":"Eco-friendly AgBiS\u2082 nanocrystals with photodetector performance. 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Topics","link":"https:\/\/tuat-chemphys.net\/?cat=9"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2025\/08\/image.png?fit=600%2C472&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2025\/08\/image.png?fit=600%2C472&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2025\/08\/image.png?fit=600%2C472&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":6895,"url":"https:\/\/tuat-chemphys.net\/?p=6895","url_meta":{"origin":5255,"position":2},"title":"\u30e9\u30dc\u30ed\u30fc\u30c6\u30fc\u30b7\u30e7\u30f3\u5236\u5ea6 Lab Rotation Program 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&quot;Event\/News&quot;","block_context":{"text":"Event\/News","link":"https:\/\/tuat-chemphys.net\/?cat=4"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/tuat-chemphys.net\/wp-content\/uploads\/2025\/10\/image-6-300x141.png?resize=350%2C200&ssl=1","width":350,"height":200},"classes":[]},{"id":7173,"url":"https:\/\/tuat-chemphys.net\/?p=7173","url_meta":{"origin":5255,"position":3},"title":"\u9178\u5316\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\u7c89\u672b\u306b\u3088\u308b\u5316\u5b66\u84c4\u71b1\u306e\u4ed5\u7d44\u307f Why MgO Powder Is a Promising Material for Thermochemical Heat Storage","author":"unet","date":"2026-01","format":false,"excerpt":"\u672c\u7814\u7a76\u3067\u306f\u3001\u9178\u5316\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\uff08MgO\uff09\u3092\u7528\u3044\u3001\u6d41\u52d5\u5c64 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SPR\u30bb\u30f3\u30b5\u30fc\uff1a\u9162\u9178\u306a\u3069\u306e\u30ab\u30eb\u30dc\u30ad\u30b7\u30eb\u57fa\u3092\u6301\u3064\u5206\u5b50\u306e\u9ad8\u9078\u629e\u7684\u691c\u51fa","author":"unet","date":"2025-11","format":false,"excerpt":"\u672c\u7814\u7a76\u306f\u3001\u8868\u9762\u30d7\u30e9\u30ba\u30e2\u30f3\u5171\u9cf4\uff08SPR\uff09\u30bb\u30f3\u30b5\u30fc\u306b\u30dd\u30ea\u30a8\u30c1\u30ec\u30f3\u30a4\u30df\u30f3\uff08PEI\uff09\u3092\u88c5\u98fe\u3059\u308b\u3053\u3068\u3067\u3001\u9162\u9178\u306a\u3069\u306e\u30ab\u30eb\u30dc\u30ad\u30b7\u30eb\u57fa\u3092\u6301\u3064\u5206\u5b50\u3092\u9ad8\u9078\u629e\u7684\u306b\u691c\u51fa\u3067\u304d\u308b\u3053\u3068\u3092\u793a\u3057\u307e\u3057\u305f\u3002This work demonstrates that decorating SPR sensors with PEI enables highly selective detection of carboxylic acid like acetic acid.","rel":"","context":"In &quot;Research Topics&quot;","block_context":{"text":"Research 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